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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg Product Name Thalidomide-O-PEG5-C2-acid Synonyms Thalidomide-4'-O-PEG5-C2-acid

SKU 2022111908
4.8
USD495.00 USD515.00

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Ships within 48 hours · Estimated delivery Aug 6 - Aug 11

Description

Product Name Thalidomide-O-PEG5-C2-acid Synonyms Thalidomide-4'-O-PEG5-C2-acid CAS Number 2353563-48-9 Related CAS Molecular Formula C26H34N2O12 Molecular Weight 566

513 SMILES OCCOCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

11 Purity (HPLC) >= 95% Solubility DMSO

Product Name Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C51H79N11O19 Molecular Weight 1150

69 SMILES Cl

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg Product Name Thalidomide-O-PEG5-C2-acid Synonyms Thalidomide-4'-O-PEG5-C2-acidSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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