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Product Name DOTA-tris(t-Bu)ester-NHS Synonyms CAS Number 819869-77-7 Related CAS Molecular Formula C32H55N5O10 Molecular Weight 669
Product Name: 5(6)-ROX azide Synonyms: 5-(and -6)-Carboxy-X-rhodamine Azide CAS Number: N/A Molecular Formula: C36H36N6O4 Molecular Weight: 616
Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB Synonyms CAS Number Related CAS Molecular Formula C42H56N8O14 Molecular Weight 896
Product Name tert-butyl 3-[4-(piperidin-4-yl)piperazin-1-yl]propanoate Synonyms 1-Piperazinepropanoic acid
93 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCCOCCOCCOCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan Size:5mg Product Name DOTA-tris(t-Bu)ester-NHS Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
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